October 27-30,2014

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 Program

 »»Oct. 27(Mon) »»Oct. 28(Tue) »»Oct. 29(Wed) »»Oct. 30(Thu) update: 2014.7.8
  <Japanese>          
Date Time 1F 2F 5F 4F
Hall Fukuju(144) Togen(144) Heian(144) Small Hall(250) Training room(84) 401(63) 402(30) 403(30) 406(30) 407(36)
Oct.
27
(Mon)		  9:00-12:00 　                    
13:30-17:30   Computational Toxicology FMO lecture
17:30-21:30      
 
Oct.
28
(Tue)


1st
day		 10:00-10:50   <Opening>
<Keynote>
Chair: Hiroshi Tanaka(Tokyo Medical and Dental Univ.)
Kohei Sawada(Eisai Co., Ltd.)
"Future perspective for ion channel drug discovery utilizing in silico and iPS cell technologies"		                
11:00-12:30   <Plenary Lecture>
Chair: Kohei Sawada(Eisai Co., Ltd.), Tomohiko Ohwada(The Univ. of Tokyo)
Hideyuki Okano(Keio Univ. School of Medicine)
"Investigation of Neural Diseases using iPS technologies and
Transgenic non-human Primates"
Yasuo Mori(Kyoto Univ.)
"TRP channels are chemo-attractive targets"
              　
12:30-13:00     <Luncheon Seminar>
Elsevier Japan KK
       12:30-
CBIJ Editing Committee		      
13:00-14:00 Poster Session  
14:00-15:30   <Symposium> "Ion Channel"
Chair: Yasuo Mori (Kyoto Univ.), Yuji Imaizumi (Nagoya City Univ.)
Yuji Imaizumi(Nagoya City Univ.)
"Ca2+ gated ion channels as molecular targets for drug discovery"
Michael Morton (AstraZeneca)
"Ion Channel Drug Discovery: TRPs and pitfalls"
Katsutoshi Ido(Eisai Co., Ltd.)
"Drug discovery research of AMPA receptor blockers: A successful case of perampanel"
<Sponsored Session>
Ryoka Systems Inc.		   Open symposium of Grant-in-Aid for Scientific Research on Innovation Area "Molecular Robotics" <Focused Session>
"Attempts to solve the ‘synapse hypoplasia’ of hiPSC-neurons by industry, government, and academia"		 <Focused Session>
"Genomic Electric Health Record"		     <Focused Session>
"Metabolomics and the first-principles calculation: prediction and
validation"		  
15:30-16:00 Poster Session                
16:00-17:30   <Symposium> "Human iPS derived differentiated cells"
Chair: Atsushi Sugiyama (Toho Univ.), Yuko Sekino(NIHS)
Ryuichi Nishinakamura (Kumamoto Univ.)
"Generation of the three-dimensional kidney structures from human iPS cells"
Koichi Nakayama (Saga Univ.)
"A New Approach for 3D Tissue & Organ Fabrication Inspired From Orthopedic Surgery"
Norimasa Miyamoto (JPMA/Eisai Co., Ltd.)
"Initiatives of the application of human iPS cell-derived cells for drug safety evaluation by pharmaceutical companies"
<The Power and Future of Pharmacometrics in Drug Development>
Chair: Takashi Mizuma (Matsuyama Univ.)
Takashi Mizuma (Matsuyama Univ.)
"The Computational Sciences and the Pharmaceutical Sciences"
Ryosei Kawai (Bayer Yakuhin, Ltd)
"Quantitative Systems Pharmacology (QSP) modeling in drug research and development: current status and perspectives"
Atsunori Kaibara (Astellas Pharma Inc.)
"Pharmacometrics--Modeling & Simulation for Clinical Endpoint"
             
17:30-18:30 Mixer 17:30-18:00   CBI General Meeting                  
18:00-18:30   CBI Council Meeting
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Date Time 1F 2F 5F 4F
Hall Fukuju Togen Heian Small Hall Training room 401 402 403 406 407
Oct.
29
(Wed)


2nd
day		 10:00-11:30   <Plenary Lecture>
Chair: Megumi Ikemori(Eisai Co., Ltd.), Yuto Komeiji (AIST)
Seiryo Sugiura(The Univ. of Tokyo)
"In silico cardiotoxicity testing using a multi-scale heart simulator UT-Heart"


Fumio Hirata(Institute for Molecular Science/Ritsumekan Univ.)
"A new method of in-silico drug screening based on combined 3D-RISM and docking algorithms"		                
11:30-13:00       <Luncheon Seminar>
World Fusion Co., LTD.		              
13:00-14:00 Poster Session                    
14:00-15:30   <Symposium>
"in silico approaches for drug targets"
Chair: Yuji Takaoka (Accelrys Inc.), Shinichi Katakura (Daiichi Sankyo RD Novare)
Takamitsu Kobayashi (Chugai Pharmaceutical)
"Lead generation and optimization of a spiroketal class of SGLT2 inhibitor CSG452 (Tofogliflozin)"
Josep Prous, Jr.(Prous Institute for Biomedical Research)
"Integrated in-silico approach to drug discovery and safety evaluation"
Kouhei Tsumoto(IMSUT)
"Thermodynamics for Ligand Screening and Design"
<Sponsored Session>
iPS PORTAL, Inc./iPS Business Promotion Unit		   Open symposium of Grant-in-Aid for Scientific Research on Innovation Area "Molecular Robotics" <Focused Session>
"Computational Toxicology and ADME/T Screening"		 <Focused Session>
"The Second Working Group Meeting on Omics-based Analysis"		       <Focused Session>
"Moving toward in silico arrhythmic assessment: The paradigm of CiPA and efforts in Japan"
15:30-16:00 Poster Session                  
16:00-17:30   <Symposium>
"in silico technologies for safety assessment"
Chair: Kazuharu Furutani (Osaka Univ.),
Junko Kurokawa (Tokyo Medical and Dental Univ.)
Megumi Ikemori(Eisai Co., Ltd.)
"New drug development system incorporating in silico technologies for safety and efficacy assessment"
Hidefumi Kasai(Certara G.K.)
"In vitro-in vivo extrapolation and prediction for cardiotoxicity using Simcyp Cardiac Safety Simulator"
Junichi Okada(The Univ. of Tokyo)
"In silico cardiotoxicity testing using heart simulator!
<Sponsored Session>
BIOBASE Japan KK /geneXplain GmbH		   "Wide database analysis and rational molecular design for in silico drug discovery"
Chair: Yuji Takaoka (Accelrys),
Yukio Tada (The Univ. of Tokyo)
Kenji Mizuguchi (NIBIO)
"From molecular mechanisms of breast cancer cell growth to novel therapeutic strategies: a new avenue opened by the prediction of protein structure and interaction"
Osamu Ichihara(Schrödinger K.K.)
"Understanding 'fuzzy' substrate recognition of proteins through thermodynamics of hydration water molecules"
      <Focused Session>
"New R&D Models for Drug Discovery-1 ~New Trends"		  
17:30-18:30 Mixer           CBI Poster Selection Meeting        
18:30-20:30       Banquet(Zuiun)              
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Date Time 1F 2F 5F 4F
Hall Fukuju Togen Heian Small Hall Training room 401 402 403 406 407
Oct.
30
(Thu)


3rd
day		 10:00-11:30   <Plenary Lecture>
Chair: Takeshi Ishikawa(Nagasaki Univ.), Yuji Mochizuki (Rikkyo Univ.)
Shigehiko Hayashi(Kyoto Univ.)
"Understanding and Design of molecular functions of flexible proteins"
Hiroshi Ishikita(The Univ. of Tokyo)
"Proton transfer reaction in hydrogen bond network in protein environments"
 


              　
11:30-12:00   Poster Award               　
12:00-13:30       <Luncheon Seminar>
Certara G.K.		             　
13:30-15:00   <Medical innovation in local communities and ICT-1>
Chair:Toshihisa Ishikawa

Toshihisa Ishikawa (NPO Personalized Medicine & Healthcare)
"Development of Personalized Medicine Platform in Local Communities "
Aizan Hirai(Chiba Cerebral & Cardiovascular Center)
"Innovation of regional medical service and ICT"
Tetsuro Miki (Hanwadaiichi Hospital)
"ICT in the super-aged society"
<Sponsored Session>
Nanion Technologies GmbH/Cytocentrics Bioscience GmbH/Biolin Scientific K.K.		   <Focused Session>
13:30-16:30
"New R&D Models for Drug Discovery-2~Call for Action"		 <Focused Session>
"Collaboration between computational chemistry and database"		 <Focused Session>
"Opinion- and information-exchanging public meeting for issues in the drug safety evaluation using human iPSC-derived cells"		     <Focused Session>
"Drug Discovery in Academics"		  
15:00-15:30 Break Closing Remarks   Break 　   　 　 　
15:30-17:00   <Medical innovation in local communities and ICT-2>
Tomiaki Morikawa(Keio Univ.)
"Current Picture and Blueprint of Health/Medical Personal Data Usage"
Seiji Iwatsu(FUJITSU LIMITED)
"ICT Supports Regional Medical Service and Welfare"
<Focused Session>
"Opinion- and information-exchanging public meeting for issues in the drug safety evaluation using human iPSC-derived cells"		   <Focused Session>
"Molecular Simulation and Design for Nano- and Biomolecular system"		          
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